The highly-fancied Stade Francais will hope their Argentinean World Cup trio can inspire them into beating Harlequins at the Stade Jean-Bouin.
World Cup star Juan Martin Hernandez, Ignacio Corleto and Rodrigo Roncero return to the fold to boost the 2005 finalists.
The French outfit endured a disappointing campaign last season and failed to reach the knock-out stages after a final round 21-20 defeat away to eventual finalists Leicester Tigers.
Harlequins return to Europe’s top competition after a two-year absence and although Dean Richards men welcome back England stars Andy Gomersall and Nick Easter, they couldn’t have asked for a more difficult start in Paris.