Pool Four leaders Harlequins face basement side the Scarlets aiming to secure a home quarter-final spot. Harlequins will be looking to avenge the defeat in Belfast last weekend and gain some momentum going into the latter stages.

The Scarlets pulled off a shock by dumping Stade Francais out of the competition with their first European win after 11 failures. Fly-half Stephen Jones will hope to impress the Wales coaches after his inclusion for the Six Nations which starts next month.