London Irish have been one of the surprise packages of the competition to date and are leading Pool 1 by one point ahead of Perpignan.

The Exiles hammered the Newport Gwent Dragons 45-17 in the reverse fixture at Rodney Parade.

And they will look to be one foot in the quarter-finals for the first time with another convincing show at the Madejski Stadium.

The Dragons all but exited the competition with a last-minute home defeat to Benetton Treviso but the Welsh region will have pride to play for.